Condemn to twisted temper (4)
I believe the answer is:
doom
'condemn' is the definition.
(I know that condemn can be written as doom)
'twisted temper' is the wordplay.
'twisted' says the letters should be written in reverse.
'temper' becomes 'mood' (synonyms).
'mood' backwards is 'DOOM'.
'to' acts as a link.
(Other definitions for doom that I've seen before include "A bad lot" , "Mood of death or ruin" , "Fate; condemn to death" , "Downfall" , "Fate; ruin" .)