Condescend to give a drunken sot work (5)
I believe the answer is:
stoop
'condescend' is the definition.
(I've seen this before)
'give a drunken sot work' is the wordplay.
'give' says to put letters next to each other.
'a drunken' is an anagram indicator.
'work' becomes 'op' (abbreviation for opus).
'sot' with letters rearranged gives 'sto'.
'sto'+'op' is 'STOOP'.
'to' acts as a link.
(Other definitions for stoop that I've seen before include "Bend the top half of the body" , "Lower one's standards" , "Condescend" , "Hunch" , "Stand bent forward" .)