Condescend to remove first of specs from blueprint (5)
I believe the answer is:
deign
'condescend' is the definition.
(synonyms)
'first of specs from blueprint' is the wordplay.
'first of specs' becomes 's' (1st letter of 'specs').
'from' is a deletion indicator.
'blueprint' becomes 'design' (synonyms).
'design' with 's' taken away is 'DEIGN'.
'to remove' is the link.
This may not be correct. Some or all of it may be part of another bit of the clue.
Can you help me to learn more?
(Other definitions for deign that I've seen before include "Think fit" , "See fit" , "Be pleased" , "consent" , "Think appropriate" .)