Confess US evil and head for Guantanamo (4)
I believe the answer is:
sing
'confess us' is the definition.
'sing' can be an answer for 'confess' (sing can informally mean to talk to the police). I'm not certain of the 'us' bit.
'evil and head for guantanamo' is the wordplay.
'evil' becomes 'sin' (synonyms).
'and' says to put letters next to each other.
'head for' indicates taking the first letters.
The first letter of 'guantanamo' is 'g'.
'sin'+'g'='SING'
Can you help me to learn more?
(Other definitions for sing that I've seen before include "Warble" , "Celebrate" , "Turn informer" , "serenade" , "Croon" .)