Confused a vacant drunkard and went in front (6)
I believe the answer is:
addled
'confused' is the definition.
(eg drug-addled)
'a vacant drunkard and went in front' is the wordplay.
'vacant' suggests removing the centre (a vacant or emptied out form of the word).
'and' says to put letters next to each other.
'went in front' becomes 'led' (I've seen this in another clue).
'drunkard' with its middle removed is 'dd'.
'a'+'dd'+'led'='ADDLED'
(Other definitions for addled that I've seen before include "Baffled - rotten" , "Perplexed -- rotten" , "mixed-up" , "Corrupt" , "Rotten; muddled" .)