Confused in game or puzzle (6)
I believe the answer is:
enigma
'puzzle' is the definition.
(I've seen this before)
'confused in game' is the wordplay.
'confused' is an anagram indicator.
'in'+'game'='ingame'
'ingame' is an anagram of 'ENIGMA'.
'or' is the link.
(Other definitions for enigma that I've seen before include "Mysteriously puzzling person or thing" , "WW two Ger. code device; puzzle" , "WWII cipher" , "German military cipher machine" , "'Mystery, riddle (6)'" .)