Confusion of curious cat losing tail (6)
I believe the answer is:
rumpus
'confusion' is the definition.
(thesaurus)
'curious cat losing tail' is the wordplay.
'curious' becomes 'rum' (synonyms).
'cat' becomes 'puss' (puss is a kind of cat).
'losing tail' means to remove the last letter.
'puss' with its last letter removed is 'pus'.
'rum'+'pus'='RUMPUS'
'of' is the link.
(Other definitions for rumpus that I've seen before include "Row" , "Noisy brawl" , "Noisy, disruptive commotion" , "Noisy disturbance" , "Uproar or angry dispute" .)