Connecticut's oldest university (4)
I believe the answer is:
yale
'connecticut's oldest university' is the definition.
(I've seen this in another clue)
This is all the clue.
(Other definitions for yale that I've seen before include "Mass. university" , "Very important university" , "Member of the 11 - type of lock" , "US Ivy League university" , "University in USA" .)