Consecrated area guarded by son and daughter (6)
I believe the answer is:
sacred
'consecrated' is the definition.
(I know that consecrated can be written as sacred)
'area guarded by son and daughter' is the wordplay.
'area' becomes 'acre' (an acre is an area of land).
'guarded by' means one lot of letters goes inside another.
'son' becomes 's' (genealogical abbreviation for son).
'and' is a charade indicator (letters next to each other).
'daughter' becomes 'd' (genealogical abbreviation).
's'+'d'='sd'
'acre' put within 'sd' is 'SACRED'.
(Other definitions for sacred that I've seen before include "Like gravestones maybe" , "Hallowed, consecrated" , "Religious" , "'Hallowed, holy (6)'" , "Sanctified" .)