Consumes drink after exercise (4,2)
I believe the answer is:
uses up
'consumes' is the definition.
('use up' can be a synonym of 'consume')
'drink after exercise' is the wordplay.
'drink' becomes 'sup' (I've seen this before).
'after' says to put letters next to each other.
'exercise' becomes 'use' ('use' can be a synonym of 'exercise'**).
'sup' put after 'use' is 'USES UP'.
(Other definitions for uses up that I've seen before include "Exhausts" , "'Depletes (4,2)'" , "Consumes" , "drains" .)