Control (4)
(Other definitions for rule that I've seen before include "Reign - law" , "Government; regulation" , "Prescribed guide for conduct" , "Control, government" , "Government - measure" .)
'control' is the definition.
(I know that rein is a type of control)
This is all the clue.
(Other definitions for rein that I've seen before include "Strap to control horse" , "Hold back" , "Free ... is carte blanche" , "kidney?" , "Harness item" .)
(Other definitions for pest that I've seen before include "Annoying thing" , "Annoying person" , "Menace" , "Disease with a high death rate" , "Troublesome person" .)
(Other definitions for self that I've seen before include "Person's distinct identity" , "A person's awareness of their own identity" , "one's identity" , "Ego, identity" , "Personality" .)
'control' is the definition.
(I know that guidance is a type of control)
This is the entire clue.
(Other definitions for guidance that I've seen before include "Leadership, direction" , "instruction" , "Help, advice or counselling" , "Direction or advice" , "Counsel; steering" .)
'control' is the definition.
(I've seen this before)
This is the entire clue.
(Other definitions for regulate that I've seen before include "Ate gruel (anag.)" , "ADjust, fix" , "Control or direct by means of rules and procedures" , "Police" , "Bring order" .)
'control' is the definition.
(I know that run is a kind of care)
This is the entire clue.
(Other definitions for run that I've seen before include "Trot" , "On the . . . - fleeing from pursuit" , "Flow quickly" , "A single" , "Unbroken series" .)
'control' is the definition.
(mastery can mean control or command of something)
This is the entire clue.
(Other definitions for mastery that I've seen before include "Expert skill" , "in full command" , "Grasp" , "Comprehensive knowledge (of a subject)" , "Supremacy" .)