Controlled squeezes make gas (5)
I believe the answer is:
radon
'gas' is the definition.
(thesaurus)
'controlled squeezes make' is the wordplay.
'controlled' becomes 'ran' (I've seen this in other clues).
'squeezes' means one lot of letters goes inside another (squeeze can mean hug or embrace).
'make' becomes 'do' (doing is a kind of making).
'ran' going around 'do' is 'RADON'.
(Other definitions for radon that I've seen before include "hazardous substance" , "Noble gas, Rn" , "Inert gas that occurs naturally" , "Element, symbol Rn" , "Colourless gas, atomic number 86" .)