Cordial, gin and ale mixed (6)
I believe the answer is:
genial
'cordial' is the definition.
(synonyms)
'gin and ale mixed' is the wordplay.
'and' says to put letters next to each other.
'mixed' is an anagram indicator.
'gin'+'ale'='ginale'
'ginale' anagrammed gives 'GENIAL'.
(Other definitions for genial that I've seen before include "'Cheerful, friendly, sociable (6)'" , "relating to the chin" , "'Affable, warm and friendly (6)'" , "Pleasant and cheerful like good host" , "Angel I found being affable" .)