Could span the only unglazed opening in this famous temple (8)
I believe the answer is:
pantheon
'temple' is the definition.
(a pantheon is a temple for multiple gods)
'could span the only unglazed opening in this famous' is the wordplay.
'PANTHEON' is hidden within the letters.
However, I'm unsure how this is indicated.
Can you help me to learn more?
(Other definitions for pantheon that I've seen before include "Ancient Roman temple" , "memorial" , "Roman building" , "list of great names" , "building that was built to honour gods" .)