Country doctor comes in with new issue (8)
I believe the answer is:
children
'issue' is the definition.
(I've seen this before)
'country doctor comes in with new' is the wordplay.
I cannot really see how this works, but
'doctor' could be 'dr' ('Dr' can be a synonym of 'doctor') and 'dr' is present in the answer.
'country' could be 'chile' (Chile is an example) and 'chile' is present in the leftover letters.
'new' could be 'n' and 'n' is found in the answer.
No letters remain.
This explanation may well be incorrect...
Can you help me to learn more?
(Other definitions for children that I've seen before include "Young people" , "Kids" , "Minors" , "Young folk" , "Youngsters" .)