Courteous E European welcoming Italian (6)
I believe the answer is:
polite
'courteous' is the definition.
(similar in meaning)
'e european welcoming italian' is the wordplay.
'e european' becomes 'Pole' (someone from Poland, an Eastern European country).
'welcoming' means one lot of letters goes inside another (in sense of 'inviting in').
'italian' becomes 'it' (abbreviation for Italian).
'pole' placed around 'it' is 'POLITE'.
(Other definitions for polite that I've seen before include "Cultured, refined" , "Cultivated" , "Respectful and considerate" , "Considerate, cultured" , "Good mannered and civil" .)