Covered up by Cesare Borgia's houppelande, for instance (4)
I believe the answer is:
robe
'instance' is the definition.
Although both the answer and definition are singular nouns, I can't see how they can define each other.
I can't explain the rest of the clue.
Can you help me to learn more?
(Other definitions for robe that I've seen before include "Formal vestment" , "Old cloak for Boer" , "Ceremonial garment, clothe" , "Loose outer garment" , "habit" .)