Crash has Queen in pain (5)
I believe the answer is:
prang
'crash' is the definition.
(I've seen this before)
'queen in pain' is the wordplay.
'queen' becomes 'r' (r is abbreviation regina. e.g. in ER ).
'in' means one lot of letters goes inside another.
'pain' becomes 'pang' (pang is a kind of pain**).
'r' put within 'pang' is 'PRANG'.
'has' acts as a link.
(Other definitions for prang that I've seen before include "Car accident, usually not too serious" , "Crash (slang)" , "Bomb attack" , "knock" , "Minor shunt" .)