Crazy artists making medium-hot curry (6)
I believe the answer is:
madras
'medium-hot curry' is the definition.
(madras is a type of curry)
'crazy artists' is the wordplay.
'crazy' becomes 'mad' (synonyms).
'artists' becomes 'RA's' (Royal Academicians abbreviation).
'mad'+'ras'='MADRAS'
'making' is the link.
(Other definitions for madras that I've seen before include "Capital city" , "Kind of curry" , "Former name of Indian city and state" , "Cotton fabric; hot curry" , "Indian city now recalled" .)