Creatures of giant stature? (4)
I believe the answer is:
ants
'creatures' is the definition.
(ant is a kind of creature)
'of giant stature?' is the wordplay.
'of' says the answer is hidden in the clue.
'ANTS' can be found hidden inside 'giant stature'.
(Other definitions for ants that I've seen before include "Soldiers" , "Busy little insects" , "Emmets" , "Inhabitants of a formicary" , "Termites" .)