Creepy English lake (5)
I believe the answer is:
eerie
'creepy' is the definition.
(eerie can mean strange or creepy)
'english lake' is the wordplay.
'english' becomes 'E' (abbreviation).
'lake' becomes 'erie' (Lake Erie is one of the Canadian/US 'Great Lakes').
'e'+'erie'='EERIE'
(Other definitions for eerie that I've seen before include "Oddly frightening" , "Awesome" , "Uncannily strange" , "Spooky, weird" , "Sinister" .)