Criminal Act renders minister powerless (5)
I believe the answer is:
arson
'criminal act' is the definition.
(arson is a crime)
I don't understand how the remainder of the clue works.
(Other definitions for arson that I've seen before include "Malicious fire-lighting" , "Torching" , "Fire requiring forensic study" , "Incendiary crime" , "Criminal activity" .)