Cry of huge animal that's audible? (4)
I believe the answer is:
wail
'cry' is the definition.
(I know that wail is a type of cry)
'huge animal that's audible?' is the wordplay.
'huge animal' becomes 'whale' (whales are large animals).
'that's audible?' indicates a 'sounds like' (homophone) clue (I've seen 'audible' mean this).
'whale' sounds like 'WAIL'.
'of' is the link.
(Other definitions for wail that I've seen before include "(Make a) plaintive cry" , "Lamentation" , "Mournful cry" , "Prolonged cry" , "Sorrowful cry" .)