Cryptic setters... they pose problems? (7)
I believe the answer is:
testers
'they pose problems?' is the definition.
'cryptic setters' is the wordplay.
'cryptic' indicates an anagram (I've seen this in other clues).
'setters' anagrammed gives 'TESTERS'.
(Other definitions for testers that I've seen before include "Streets (anag.)" , "They conduct examinations" , "guinea pigs" , "Bed canopies" , "Samples of perfume" .)