Cunning in trade cultivated (7)
I believe the answer is:
trained
'cultivated' is the definition.
('train' can be a synonym of 'cultivate')
'cunning in trade' is the wordplay.
'cunning' indicates anagramming the letters.
'in'+'trade'='intrade'
'intrade' anagrammed gives 'TRAINED'.
(Other definitions for trained that I've seen before include "Taught, educated" , "Taught (to do a job)" , "Did exercises" , "Schooled" , "Instructed - took aim" .)