Curse affected sheep and lamb (9)
I believe the answer is:
blaspheme
'curse' is the definition.
(synonyms)
'affected sheep and lamb' is the wordplay.
'affected' indicates anagramming the letters.
'and' says to put letters next to each other.
'sheep' after 'lamb' is 'lambsheep'.
'lambsheep' is an anagram of 'BLASPHEME'.
(Other definitions for blaspheme that I've seen before include "Talk irreverently about God and sacred things" , "Speak irreverently about God" , "Utter obscenities or profanities" , "Say irreverent things about God" , "Curse profanely" .)