Cursed swindle set up (10)
I believe the answer is:
confounded
'cursed' is the definition.
(thesaurus)
'swindle set up' is the wordplay.
'swindle' becomes 'con' (con is a kind of swindle).
'set up' becomes 'founded' (I've seen this in other clues).
'con'+'founded'='CONFOUNDED'
(Other definitions for confounded that I've seen before include "Perplexed - damned" , "Brought to confusion" , "Really annoying (nuisance)" , "Confused; astonished" , "ending of Te Deum?" .)