Daisy, perhaps, works on US TV series (6)
I believe the answer is:
miller
'daisy' is the definition.
(Daisy Miller is a novel by Henry James)
'works on us tv series' is the wordplay.
'works' becomes 'mill' (mill is a kind of works).
'on' says to put letters next to each other.
'us tv series' becomes 'ER' (US medical drama).
'mill'+'er'='MILLER'
'perhaps' acts as a link.
(Other definitions for miller that I've seen before include "American playwright" , "Grain-grinder" , "Cereal worker" , "His salesman died" , "Grain grinder" .)