Dame mad about cheese (4)
I believe the answer is:
edam
'cheese' is the definition.
(I know that Edam is a type of cheese)
'dame mad' is the wordplay.
'mad' indicates anagramming the letters.
'dame' anagrammed gives 'EDAM'.
'about' acts as a link.
(Other definitions for edam that I've seen before include "Yellow cheese with a red covering" , "town in Holland" , "Kind of cheese" , "Cheese made in Holland" , "edible sphere" .)