Damned ringleader framed by one on trial (8)
I believe the answer is:
accursed
'damned' is the definition.
(I've seen this before)
'ringleader framed by one on trial' is the wordplay.
'ringleader' becomes 'r' (first letter of ring).
'framed by' is an insertion indicator.
'one on trial' becomes 'accused' (I've seen this in another clue).
'r' going inside 'accused' is 'ACCURSED'.
(Other definitions for accursed that I've seen before include "Goddamn" , "Cue cards (anag) - doomed" , "Wretched" , "Hateful" , "Detestable (colloq.)" .)