Dandy, 50, taking refuge in wicked Southern city (9)
I believe the answer is:
nashville
'southern city' is the definition.
'Nashville' can be an answer for 'city' (Nashville is an example). I am not sure about the 'southern' bit.
'dandy 50 taking refuge in wicked' is the wordplay.
'dandy' becomes 'nash' (I've seen this before).
'50' becomes 'l' ('L' can be a synonym of '50').
'taking refuge in' is an insertion indicator.
'wicked' becomes 'vile' ('vile' can be similar in meaning to 'wicked'**).
'l' going inside 'vile' is 'ville'.
'nash'+'ville'='NASHVILLE'
Can you help me to learn more?
(Other definitions for nashville that I've seen before include "country town" , "Capital of Tennessee and home of country music" , "Centre of country and western" , "Where the Grand Ole Opry comes from" , "US city" .)