Darn pain! (6)
I believe the answer is:
stitch
I believe this is a double definition.
'darn' is the first definition.
(I've seen this before)
'pain' is the second definition.
(pain in the body)
(Other definitions for stitch that I've seen before include "Loop of thread" , "Sharp pain in the side brought on by running" , "Link, loop or knot made in knitting or sewing" , "in time one could save many" , "result of working with needle?" .)