Daughter one having bad experience (6)
I believe the answer is:
downer
'bad experience' is the definition.
(I've seen this in another clue)
'daughter one having' is the wordplay.
'daughter' becomes 'd' (genealogical abbreviation).
'one having' becomes 'owner' (I've seen this before).
'd'+'owner'='DOWNER'
(Other definitions for downer that I've seen before include "In slang, a depressant drug" , "Informally a depressant drug" , "Sedative" , "Depressing experience" , "Saddening experience" .)