Daughter with strange instrument (4)
I believe the answer is:
drum
'instrument' is the definition.
(drum is a kind of instrument)
'daughter with strange' is the wordplay.
'daughter' becomes 'd'.
'with' says to put letters next to each other.
'strange' becomes 'rum' (I've seen this before).
'd'+'rum'='DRUM'
(Other definitions for drum that I've seen before include "Percussion instrument" , "Iris rootstock (perfume)" , "Spool; beaten instrument" , "one will be beaten" , "Introductory beats" .)