De luxe hotel a good thing to open (5)
I believe the answer is:
plush
'de luxe' is the definition.
(both can mean fancy or high-quality)
'hotel a good thing to open' is the wordplay.
'hotel' becomes 'h' (phonetic alphabet: alpha, bravo, charlie etc.).
'a good thing' becomes 'plus' (I've seen this in another clue).
'to open' is a charade indicator (letters next to each other) (some letters go before or 'open' others).
'h' after 'plus' is 'PLUSH'.
(Other definitions for plush that I've seen before include "Fabric; richly luxurious" , "Fabric with a long velvety pile" , "Cut pile, softer than velvet" , "Rich fabric" .)