Dead ends — eccentric made unhappy (8)
I believe the answer is:
saddened
'made unhappy' is the definition.
(I've seen this before)
'dead ends eccentric' is the wordplay.
'eccentric' indicates anagramming the letters.
'dead'+'ends'='deadends'
'deadends' is an anagram of 'SADDENED'.
(Other definitions for saddened that I've seen before include "Distressed" , "Made sorrowful" , "unhappiness" , "Made unhappy or melancholy" .)