Deal with again? Deal with her afresh around noon (8)
I believe the answer is:
rehandle
'deal with again?' is the definition.
('handle' can be a synonym for 'deal with' so perhaps 'rehandle' is OK for 'deal with again')
'deal with her afresh around noon' is the wordplay.
'with' means one lot of letters go next to another.
'afresh' indicates anagramming the letters.
'around' indicates putting letters inside.
'noon' becomes 'n' (abbreviation for noon).
'deal'+'her'='dealher'
'dealher' with letters rearranged gives 'rehadle'.
'rehadle' placed around 'n' is 'REHANDLE'.
(Another definition for rehandle that I've seen is " Manage again".)