Debate again about fever acquiring resistance (7)

'debate again' is the definition.
('argue' can be a synonym for 'debate' so perhaps 'reargue' is OK for 'debate again')

'about fever acquiring resistance' is the wordplay.
I cannot quite understand how this works, but
'about' could be 'rea' (I've seen this in other clues) and 'rea' is present in the answer.
'resistance' could be 'r' (abbreviation in physics and electronics) and 'r' is located in the answer.
The remaining letters 'gue' is a valid word which might be clued in a way I don't understand.
This may be the basis of the clue (or it may be nonsense).

Can you help me to learn more?