Debauched renegade worried Lawrence (10)
I believe the answer is:
degenerate
'debauched' is the definition.
('degenerate' can be a synonym of 'debauched')
'renegade worried lawrence' is the wordplay.
'worried' is an anagram indicator.
'lawrence' becomes 'te'.
'renegade' is an anagram of 'degenera'.
'degenera'+'te'='DEGENERATE'
(Other definitions for degenerate that I've seen before include "Reprobate" , "Rogue" , "Immoral" , "Corrupt type" , "Debased, degraded" .)