Deeply thoughtful, keen to raise issue (6)
I believe the answer is:
broody
I believe this is a double definition.
'deeply thoughtful' is the first definition.
(to brood is to engage in deep thought)
'keen to raise issue' is the second definition.
(issue can mean a person's offspring)
(Other definitions for broody that I've seen before include "Ready and wanting to have children" , "Ready to incubate eggs" , "Pensive" , "Morbidly thoughtful" , "Thoughtful, unhappy" .)