Defeat the formation of much unsafe flab (6)
I believe the answer is:
baffle
'defeat' is the definition.
(thesaurus)
I can't explain the remainder of the clue.
Can you help me to learn more?
(Other definitions for baffle that I've seen before include "Perplex and bewilder" , "Damper - foil" , "Dumbfound" , "Puzzle - foil" , "Mystify, bewilder" .)