Deleting Regina's mistake (7)
I believe the answer is:
erasing
'deleting' is the definition.
(erasing is a kind of deleting)
'regina's mistake' is the wordplay.
'mistake' is an anagram indicator.
'reginas' with letters rearranged gives 'ERASING'.
(Other definitions for erasing that I've seen before include "obliterating memory" , "Removing" , "Getting rid of" , "Rubbing out" .)