Deliberately miss Italian title, having thrown away lead (6)

I believe the answer is:

ignore

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'deliberately miss' is the definition.
'ignore' can be an answer for 'miss' (thesaurus). I'm not sure about the 'deliberately' bit.

I don't understand how the rest of the clue works.

Can you help me to learn more?

(Other definitions for ignore that I've seen before include "set aside" , "Refuse to notice or acknowledge" , "Dismiss" , "Intentionally disregard" , "Region (anag)" .)

I've seen this clue in The Telegraph.

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