Denotes high-pitched instrument used three times (6)
I believe the answer is:
treble
'times' is the definition.
Although both the answer and definition are singular nouns, I don't understand how one could define the other.
I don't understand the rest of the clue.
Can you help me to learn more?
(Other definitions for treble that I've seen before include "Triple - high-pitched" , "High-frequency (radio control knob)" , "High darts score" , "Triple - soprano voice" , "large measure" .)