Deny diva, so distraught over wife (7)
I believe the answer is:
disavow
'deny' is the definition.
(I know that disavow is a type of deny)
'diva so distraught over wife' is the wordplay.
'distraught' indicates an anagram.
'over' is a charade indicator (letters next to each other).
'wife' becomes 'w'.
'diva'+'so'='divaso'
'divaso' with letters rearranged gives 'disavo'.
'disavo'+'w'='DISAVOW'
(Other definitions for disavow that I've seen before include "Disclaim" , "To deny support" , "Refuse to acknowledge" , "Deny responsibility for (something)" , "To deny knowledge of" .)