Depended on again, deceived one (6)
I believe the answer is:
'depended' is the definition.
(I've seen this in another clue)
'on again deceived one' is the wordplay.
'on' means one lot of letters go next to another.
'again' becomes 're'.
'deceived one' becomes 'lied' (I can't explain this - if you can you should give a lot more credence to this answer).
're' next to 'lied' is 'RELIED'.
Can you help me to learn more?
(Other definitions for relied that I've seen before include "Banked" , "Was dependent (on)" , "Depended on or fibbed again" , "Had confidence" , "Assembled as before" .)