Derelict roadhouse cleaned out by maid (6)
I believe the answer is:
remiss
'derelict' is the definition.
(I know that derelict can be written as remiss)
'roadhouse cleaned out by maid' is the wordplay.
'cleaned out' suggests removing the centre.
'by maid' becomes 'miss' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'roadhouse' with its centre taken out is 're'.
're'+'miss'='REMISS'
Can you help me to learn more?
(Other definitions for remiss that I've seen before include "Derelict in duty" , "Negligent, slack" , "Negligent, derelict" , "Neglectful" , "Failing in one's duty" .)