Deride US city that’s disgusting and extremely affluent (5,2)

'deride' is the definition.
(I've seen this in another clue)

'us city that's disgusting and extremely affluent' is the wordplay.
'us city' becomes 'LA' (Los Angeles).
'that's disgusting' becomes 'ugh' (expression of disgust).
'and' says to put letters next to each other.
'extremely' means to remove the middle letters (only the extremes of the word are used).
'affluent' with its centre taken out is 'at'.
'la'+'ugh'+'at'='LAUGH AT'