Descartes has a disfigurement (4)
I believe the answer is:
scar
'a disfigurement' is the definition.
(I've seen this before)
'descartes has' is the wordplay.
'has' indicates the answer is hidden within the clue.
'SCAR' can be found hidden inside 'descartes'.
(Other definitions for scar that I've seen before include "Stigma" , "Gordale - - , Yorks" , "Healed-cut mark" , "Sign of old injury" , "Leave wound mark" .)