Design original clothing for Italian? (6)
I believe the answer is:
signor
'for italian?' is the definition.
(Italian equivalent of 'mister')
'design original clothing' is the wordplay.
'clothing' says the answer is hidden in the clue (the solution is covered or clothed by the clue).
'SIGNOR' is hidden within 'design original'.
(Other definitions for signor that I've seen before include "Italian gentleman" , "Italian mister" , "Title of Italian-speaking man" , "Title of Italian man" , "Guy in Rome" .)